MeAgain IndexQ1 2026

Zepbound and Mounjaro, both from Lilly, take first and second place on the first Leading GLP-1 Meds list. Not only are they among the most used GLP-1s on the MeAgain platform, but members on Zepbound also recorded one of the highest median weight losses for the quarter in our real-world dataset. The continued demand for Lilly medicines came as Lilly lowered out-of-pocket costs, cutting Zepbound vial prices in December, launching the KwikPen at the same price in Q1 and listing Zepbound on TrumpRx from $299. Direct-to-consumer GLP-1s have continued to go mainstream. One in three new patients starting a branded weight-loss drug in 2025 began on Zepbound self-pay vials.

Compounded tirzepatide completes the top three. Its share of new members rose 20% from the end of 2025, making it the most common GLP-1 of choice for new members this quarter. The rise came as four state Medicaid programs stopped covering GLP-1s for weight loss in January, and it is not just Medicaid that is pulling back. The share of large employers covering the drugs for weight loss has fallen from 72% in 2025 to 60% this year.

+20%rise in compounded tirzepatide's share of new MeAgain members in Q1 2026

Fiber joins protein on the list. Consumption of :ratio's Lemon Meringue Pro-Fiber yogurt rose 316%, and its Blueberry flavor rose 153%, in their first full quarter on sale. Lactalis (parent company of :ratio) launched the snack nationwide in November and sold it as GLP-1 friendly. The timing was right. In January, CNN called fiber the next big thing after protein.

Protein snacks reached more shoppers. David went nationwide at Target and Walmart in the first quarter. Consumption of its Chocolate Chip Cookie Dough bar rose 232%, landing it in sixth place, while its Peanut Butter Chocolate Chunk bar, tenth, rose 164%. Simply Fuel's protein balls, ninth, rose 148%.

Eight of the ten trending products this quarter are built around protein or fiber, from coffee shakes and bars to snack balls, yogurt and a high-fiber bagel from Sola in seventh place. Big food makers are chasing the same shift. PepsiCo, Coca-Cola and Nestlé are all adding high-fiber products. People on a GLP-1 eat less, so they look for more protein and fiber in every portion.

+316%rise in consumption of :ratio Pro-Fiber Lemon Meringue among MeAgain members in Q1 2026

Grüns, in 11th place, had the biggest rise in consumption of any brand on the list, up 10% for the quarter, and it was a big quarter for the brand on the retail side too, with its greens gummies landing at H-E-B, Hy-Vee and Wegmans in January and February, then at Costco nationwide in March. Nurri comes in eighth and is getting a lot more attention, with mentions of it in GLP-1 social posts up 57% after its first ad campaign in January and a move into Target in March.

A few of the names on the list have been around for decades. Great Value, Walmart's own label, comes in 12th and is one of the most consumed brands on the MeAgain platform, which shows our members are not only buying specialty brands. Mission takes seventh and draws the most positive GLP-1 social posts of any brand on the list after it pitched its tortillas for simple meals for people on GLP-1s in January. Daisy is 13th, and its cottage cheese has been selling well of late, with sales up 25% in the year ending in February, while in January the brand also ran new ads calling it a protein-packed essential.

We are also seeing the brands that started out with protein bars branch out into new formats. Quest, in fifth place, launched new Crispy Protein Chips at Walmart on March 2nd. Barebells, ninth, put its milk drink into about 2,000 Walmarts in January. Protein is moving beyond the bar, so bar brands now compete with chip and drink makers too.

+57%rise in mentions of Nurri in GLP-1 social posts in Q1 2026