GLP-1 Dose Plotter for Ozempic, Wegovy, Mounjaro & Zepbound

Ozempic and Wegovy both contain semaglutide, with an FDA-label half-life of about 1 week, so most of a dose clears in about 5 weeks. For the full timeline, dose-by-dose, see the Ozempic half-life calculator or Wegovy half-life calculator.

Mounjaro and Zepbound both contain tirzepatide, with an FDA-label half-life of about 5 days, so most of a dose clears in about 25 days. For the full timeline, dose-by-dose, see the Mounjaro half-life calculator or Zepbound half-life calculator.

About 5 weeks for most of it. With a half-life of about 1 week, roughly 97% of a semaglutide dose is gone after five half-lives, and the FDA Wegovy label says semaglutide stays in circulation for about 5 to 7 weeks after the last 2.4 mg dose. Scrub this calculator's timeline forward to watch your own estimate fade toward zero.

Roughly 25 days for most of it. With a half-life of about 5 days, about 97% of a tirzepatide dose is gone after five half-lives, so the estimate sits near zero around 4 weeks after your last shot.

Yes, by design. Weekly shots overlap: part of last week's dose is still present when the next one lands, so the level climbs across the first several weeks and then levels off. The FDA Zepbound label reports steady tirzepatide levels after about 4 weeks of once-weekly dosing. The calculator's chart shows that build-up from your own dates.

No. There is no established way to flush semaglutide or tirzepatide out faster. Water, exercise, or fasting will not meaningfully change the elimination rate; the medication clears on its half-life schedule. If side effects are the concern, that conversation belongs with your prescriber.

Ask your prescriber or pharmacist. The right step depends on which medication you take and how late you are, and the FDA labels give different instructions for each one. This calculator will not tell you what to do. It only shows how the estimate from your logged shots keeps declining the longer you wait.

A GLP-1 dose plotter charts how the amounts from your logged shots build up and taper over time. This one covers semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) injections; GLP-1 is the everyday name for the class, so that is the name the tool uses. If you mainly want to know how long a dose stays in your system after your last shot, the GLP-1 half-life calculator answers that directly.

Yes. Brand versions preset the right molecule and use the same math as this page: the Ozempic half-life calculator, Wegovy half-life calculator, Mounjaro half-life calculator, and Zepbound half-life calculator.

No. It shows a simple amount-remaining estimate, not a blood, plasma, or serum concentration. It does not model absorption, bioavailability, personal metabolism, health conditions, or interactions with other medications.

7 days. The current FDA Wegovy label describes injectable semaglutide's elimination half-life as approximately 1 week. In the chart, that is why a weekly shot lands while about half of the previous dose's estimate is still present, and why the curve builds for the first several weeks.

5 days. The FDA Zepbound label describes tirzepatide's half-life as approximately 5 days in one section and 5 to 6 days in another; the calculator uses the lower published value. At that pace, half of a dose's estimate is gone every 5 days, which is why the tirzepatide curve tapers faster between weekly shots than the semaglutide curve.

No. It does not calculate doses, missed-dose timing, dose changes, or schedules, and it never should. Follow your prescription, and bring dosing questions to a licensed clinician or pharmacist.

The estimate fades on the half-life clock: for semaglutide, about half of the last dose's contribution is gone each week and roughly 97% after about 5 weeks; for tirzepatide, half every 5 days and roughly 97% after about 25 days. As the level falls, appetite commonly returns, and published follow-up studies report that regaining weight is common. The calculator shows the fade; what stopping means for you belongs with your prescriber.

The half-life is why a switch involves an overlap window: a week after a semaglutide shot, about half of that dose's estimate is still present. The calculator can show the old medication fading, but switch timing follows label rules and is a prescribing decision for your clinician or pharmacist.

No. The calculator runs in your browser tab. Your entries are never placed in the URL, sent to MeAgain's servers, or included in analytics.

This page gives you one private estimate. The app keeps the whole picture: injection history, reminders, injection sites, symptoms, food, water, protein, fiber, weight, and progress over time.